From Futurama, Episode "The Why of Fry", after Fry learns that his reason for being frozen for 1000 years was because he was the only one who could save the universe:
Nibbler [on screen]: We had no choice. You were the only one who could help us. What is one life weighed against the entire universe?
Fry: But it was my life.
There is something deep in those words.